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In SCCM 2012 Applications you can have a detection method set for MSU with KB numbers. You can use the Powershell or VBScript to do this. Here is an example of both. Powershell Script: get-hotfix | Where-Object {$_.HotFixID -match "KB981603"} VBScript: 'Returns info if Windows 'KB981603'  in installed ' ----------------------------------------------------------' Option Explicit Dim objWMIService, strComputer strComputer = "." 'Run the query Set objWMIService = GetObject("winmgmts:" _     & "{impersonationLevel=impersonate}!\\" _     & strComputer & "\root\cimv2")   Dim QFEs Dim QFE Set QFEs = objWMIService.ExecQuery ("Select * from win32_QuickFixEngineering where HotFixID like 'KB981603'") For Each QFE in QFEs     Wscript.echo "Update KB981603 was installed by " & QFE.InstalledBy & " on " & QFE.InstalledOn Next WScript.Quit

This script has worked good for me and I would like to share with all. Option Explicit     Dim intHive     Dim strComputer     Dim strKeyPath, objRegistry     Const HKEY_CLASSES_ROOT        = &H80000000     Const HKEY_CURRENT_USER    = &H80000001     Const HKEY_LOCAL_MACHINE    = &H80000002     Const HKEY_USERS        = &H80000003     Const HKEY_CURRENT_CONFIG    = &H80000005     'On Error Resume Next     strComputer            = "."     intHive                = HKEY_LOCAL_MACHINE       strKeyPath            = "SOFTWARE\Microsoft\Windows\CurrentVersion\Explorer\ABC\XYZ"     Set objRegistry        = GetObject("winmgmts:\\" & strComputer & "\...